“To see this effect, you would need to drink a lot of green tea,” stressed study author Susanne Henning, a registered dieticianand adjunct professor with the University of California, Los Angeles David Geffen School of Medicine. “Two cups a day is not going to help. In fact, we had our men drink six cups spread out all throughout the day, which I think was beneficial because green tea polyphenols are excreted very rapidly, so if you drink it that way you keep your levels up. And that seems to be the important factor in keeping the protection going.”
To explore the anti-cancer potential of green tea, the authors focused on 67 prostate cancer patients, all of whom were weeks away from surgery. About half the men were randomly assigned to a six-cup-a-day regimen of green tea leading up to surgery, while the others consumed water instead.
The result: Blood and urine samples analyzed alongside tissue samples taken during surgery revealed that the green tea group fared significantly better on key signs of inflammation, PSA levels and expression and DNA damage.
However, no notable difference was found between the two groups in terms of tumor cell growth.
Henning stressed the need for more research on the potential green-tea/prostate cancer connection, and her team is currently planning new animal investigations involving combinations of green tea and other natural foods.
While this research showed an association between green tea and prostate cancer, it did not prove a cause-and-effect link.
“Actually, several food agents have been under investigation for their protective impact,” she noted. “Lycopene and omega-3 fatty acids, for example. So, I would say that if you have cancer and you want to make a decision about all of this, then think of incorporating all of those as a part of a lifestyle change. I know that if I was diagnosed with prostate cancer, I would try to change my lifestyle. And that would mean, in addition to eating lots of fruits and vegetables and trying to lose weight and exercising, that I would definitely drink green tea.”
The University of Miami’s Soloway said that while drinking green tea probably does not have a downside, this “limited study” does not confirm its impact as a prostate cancer intervention.
“[There’s] not much solid data to prove it,” he said. “This is a small study, and it would take a longer study with hundreds of patients to ‘prove’ its benefit.”
Soloway also noted that the jury is still out on whether inflammation even plays a significant role in cancer development. “It is very much a question,” he said. “Not proven at all.”
But, he agreed that until larger studies come along to explore green tea’s potential, “it might be worth giving it a shot.”
For more on prostate cancer risk, visit the American Cancer Society.
SOURCES: Susanne Henning, Ph.D., R.D., adjunct professor, David Geffen School of Medicine, University of California, Los Angeles; Mark Soloway, M.D., professor and chairman emeritus, urology, University of Miami Miller School of Medicine; Oct. 17, 2012, presentation, American Association of Cancer Research annual prevention conference, Anaheim, Calif.